Strouthos I, Tselis N, Zamboglou N, et al.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. Date of publication 2016 Oct 1;volume 192(10):730-6.
1. Strahlenther Onkol. 2016 Oct;192(10):730-6. doi: 10.1007/s00066-016-0984-x. Epub
2016 Jun 10.
Docetaxel-induced radiation recall dermatitis : A case report and literature
review.
Strouthos I(1), Tselis N(2), Zamboglou N(2).
Author information:
(1)Strahlenklinik, Sana Klinikum Offenbach, Starkenburgring 66, 63069, Offenbach,
Germany. jstrouthos@gmail.com.
(2)Strahlenklinik, Sana Klinikum Offenbach, Starkenburgring 66, 63069, Offenbach,
Germany.
Radiation recall dermatitis (RRD) refers to an acute inflammatory skin reaction
appearing on a previously irradiated area following the systemic administration
of a reaction-triggering agent. Despite various hypotheses, the pathomechanism of
RRD appears complex and is still not fully understood. In addition, no clinical
guidelines exist concerning whether drug treatment should be continued upon
manifestation of an associated radiation recall phenomenon. We present the case
of a patient with docetaxel-induced RRD, which was successfully treated with
topical steroids and systemic antihistamines; re-challenge to docetaxel did
result in very mild remanifestation of skin reactions.
DOI: 10.1007/s00066-016-0984-x
PMID: 27287082 [Indexed for MEDLINE]